Medical Publications

• "Prevention of Diabetes for up to 13 Years by Autoislet Transplantation After Pancreatectomy for Chronic Pancreatitis," R. Paul Robertson, Karla J. Lanz, David E.R. Sutherland, and David M. Kendall, Diabetes 50:47-50, January 2001.

Summary: Patients with chronic pancreatitis who undergo total pancreas resection inevitably become diabetic unless their islets are autotransplanted to prevent diabetes.  The study indicated that auto-islet transplantation can successfully maintain stable Beta-cell function and normal levels of blood glucose and HbA1c for up to 13 years after total pancreatectomy as treatment for chronic pancreatitis.

• "Autotransplantation of Dispersed Pancreatic Islet Tissue Combined with Total or Near-Total Pancreatectomy for Treatment of Chronic Pancreatitis," Alan C. Farney, M.D., John S. Najarian, M.D., Raouf E. Nakhleh, M.D., Goncal Lloveras, M.D., M. Jane Field, B.S., Paul F. Gores, M.D., and David E.R. Sutherland, M.D., Ph.D., Surgery 1991; 110: 427-439.

Summary: Auto-islet transplantation can be an effective and safe adjunct to extensive pancreatic resection for those patients who risk surgical diabetes for relief of their chronic pancreatitis pain.

• "Autologous Islet Transplantation to Prevent Diabetes After Pancreatic Resection," David C. Wahoff, M.D., Basil Papalois, M.D., Ph.D., John S. Najarian, M.D., David M. Kendall, M.D., Alan C. Farnay, M.D., John P. Leone, M.D., Ph.D., Jose Jessurun, M.D., David L. Dunn, M.D., Ph.D., R. Paul Robertson, M.D., David E.R. Sutherland, M.D., Ph.D., Annals of Surgery 1995; 222, 4, 562-579.

Summary: Pancreatectomy can relieve intractable pain caused by chronic pancreatitis.  Auto-islet transplantation is safe and can prevent long-term diabetes in more than 33% of patients and should be an adjunct to any pancreatic resection.  A given patient's probability of success can be predicted by the morphologic features of the pancreas.

• "Transcontinental shipping of pancreatic islets for autotransplantation after total pancreatectomy," J.M. Rabkin, J.P. Leone, David E.R. Sutherland, A. Ahman, M. Reed, B. Papalois, D.C. Wahoff, Pancreas 1997; 15:416-419.

Additional articles on pancreatectomy and auto-islet transplantation can be found on MedPub.