Inclusion and Exclusion Criteria

Inclusion Criteria

In order to qualify for an islet transplant trial at the University of Minnesota, you must meet the following criteria:

• Type 1 diabetes for more than 5 years (click here) to help determine if you are unsure which type of diabetes you have
• Age 18 to 65
• Weight 180 pounds or less
• Must have seen diabetes care team (endocrinologist, nurse educator, and dietitian) at least 3 times in the past year
• Must be checking blood sugar at least 3 times per day
• Must be giving at least 3 insulin injections per day (or using an insulin pump)
• Must have some complications (such as not having symptoms when blood sugar is low, protein in your urine, or needing laser therapy of your eyes)

If your application demonstrates that you meet these criteria, you will be contacted and additional screening may be conducted to further determine your eligibility.

Exclusion Criteria

Any of the following situations will exclude you from being able to participate in an islet transplant trial at the University of Minnesota at this time:

• Females who are currently pregnant, intend to get pregnant, or are presently breast-feeding
• Males who intend to father children
• Active or past infection with hepatitis C, hepatitis B, HIV, or TB (or under treatment for suspected TB)

• Any history of cancer except for adequately treated skin cancer

• Heart attack within the past 6 months or extensive coronary artery disease
• Under treatment for a medical condition requiring chronic use of steroids such as prednisone

Please do not be discouraged if you do not currently meet these criteria. We are working very hard to expand the criteria as much as possible so that, in the future, everyone with type 1 diabetes can eventually benefit from an islet transplant, if they so choose. Go ahead and complete the registration form. By doing so, your information will be included in our database and reviewed as new clinical trials open up and our inclusion criteria are expanded.