Qualification: The PNI focuses on the training of pre-doctoral and postdoctoral fellows in areas that intersect four disciplines: Pharmacology, Psychology, Neuroscience, and Microbiology/Immunology. Predoctoral and postdoctoral candidates who are sincerely committed to a research career in the field of Neuroimmune/Neurobehavior Addiction Research, which emphasizes the effects of drug abuse will be eligible for support by the training program. Committment of candidates will be reflected by the design of their curriculum and proposed thesis in the case of predoctoral fellows and by the candidate's willingness and enthusiasm to develop and enroll in a selection of appropriate supplementary courses. Predoctoral candidates must have earned a bachelor degree and be accepted into one of the following University of Minnesota Graduate Programs: Pharmacology, Neuroscience, Psychology, Medicinal Chemistry, or Veterinary Medicine, and be interested in interdisciplinary aspects of addiction-related research. Postdoctoral candidates must have a Ph.D., D.V.M., or M.D. and be interested in laboratory-based neuroimmune/neurobehavior addiction research. Since this program is a 100% federally funded grant, only U.S. citizens and those foreign nationals who possess a permanent residency visa (green card) may be supported by this program.