RAR’S STANDARD POST-OPERATIVE ANALGESIA

RAR’S STANDARD POST-OPERATIVE ANALGESIA

For Post-Operative Pigs, Sheep, and Dogs

NOTE: This is the routine plan, subject to modification. RAR vets will alter the analgesic plan when medically indicated.

If administration of any of these medications would interfere with your study, and you have IACUC approval to use another analgesia regimen, please notify the Post-Op vet tech. The vet tech will also note this restriction in RAR’s medical record for the animal.

SPECIES	SURGICAL PROCEDURE
SPECIES	Skin Incision Only: OPIOID [3 Days]	Entering Body Cavity/Joint: *OPIOID + NSAID [3 Days]**	Thoracotomy/Sternotomy: *OPIOIDS + NSAID [3 Days]**
Dog	Buprenorphine (0.3 mg/ml)	Buprenorphine + Rimadyl	Fentanyl + Rimadyl (+Buprenorphine on 1st day)
Pig/Sheep	Buprenorphine (2 mg/ml)	Buprenorphine + Ketoprofen	Fentanyl + Ketoprofen (+Buprenorphine on 1st day)

DOSES & USAGE:

NSAIDs*

Dose & Route

Frequency & Usage Notes

Rimadyl® (carprofen)

2 mg/kg PO or SC

q24hrs.

Can give half dose q12hrs.

Ketofen® (ketoprofen)

1-2 mg/kg PO, SC, IV, or IM

q24hrs.

Give 2 mg/kg 1st dose, then 1 mg/kg thereafter.

*The use of NSAIDS may be contraindicated where animals are already receiving anticoagulants or where coagulant response is an important part of the protocol. NSAIDs should be used with caution in animals undergoing gastric procedures. Verify NSAID use with Group and/or RAR veterinarian.

OPIOIDS

Dose & Route

Frequency & Usage Notes

Buprenex® (0.3 mg/ml)

(Buprenorphine)

0.01 mg/kg IM (Dog)

Administer q4hrs day of surgery.

Animal receives a minimum of 2 doses on day of surgery. Last dose given by RAR is 6:30pm. If another later dose is needed, group will give. After that, use BID prn (unless a Fentanyl patch is in use).

Buprenorphine

(2 mg/ml)

0.01 mg/kg IM (Sheep)

0.03 mg/kg IM (Pig)

Fentanyl Transdermal

2.5-5 mcg/hr per kg

Example:

10-20kg: use 50mcg/hr patch

20-30kg: use 75mcg/hr patch

30-40kg: use 100mcg/hr patch

(Combine patches as needed for increased weight)

Applied day of surgery. Removed after 3 days.

Supplement on first day of Fentanyl patch with Buprenorphine (see Buprenorphine usage notes above)

If animals are anticipated to be painful after Post-Op closes (7 pm) or an additional treatment is needed, RAR will notify group as soon as possible so that investigators can plan to come in to administer a dose of analgesic later in the evening. Animals recovered after 7 pm that have had an abdominal or thoracic surgery will need a second dose of Buprenorphine administered by the group 4-6 hours after recovery.