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Rodent (<50 grams) Tail Snip Guidelines

Amputation of the distal tail is often performed as a means of obtaining tissue for genetic monitoring in rodents.  While this procedure is momentary it involves a variety of tissues, including bone or cartilage, blood vessels, nervous tissue and skin.  There is potential for immediate and longer-term pain from this procedure.  The distal end of the tail is largely devoid of most of these tissues except skin.  Therefore, use of techniques that require less than 1 cm of tail to be removed is strongly encouraged for all age animals. 

Appropriate sedation or local anesthesia is also suggested. 

Removal of more than 1 cm or tail snipping in large rodents is only allowed in exceptional cases and requires scientific justification and PRIOR approval of the Institutional Animal Care and Use Committee. 

Examples of alternate methodologies include PCR assays that can be performed using blood, saliva, ear biopsy or very small tail biopsies.  Please contact an RAR veterinarian for consultation on these methods or on anesthetic selection.



The information contained in this site is intended as a reference for University of Minnesota investigators, and animal husbandry and veterinary staff. Drug information and dosages are derived from a variety of sources and do not necessarily guarantee safety or efficacy. Information obtained through this site should not be relied upon as professional veterinary advice. Any medications administered or procedures performed on animals should only be performed by or under order of a qualified, licensed veterinarian.