| Title |
Principal Investigator(s) |
College |
Request |
|
FRD 2008 Grant Summary
|
|
Molecular Characterization of Osteosarcoma: A Comparative Genomics Approach
|
Subbaya Subramanian, Ph.D.; Jaime Modiano, VMD, Ph.D.
|
Medical, Vet Med
|
$200,000
|
|
Genotype Associations with Disease Outcomes: Using Targeted SNP Genotyping to Assess Risk and Response in Lung Cancer
|
Brian Van Ness, Ph.D.; Timothy Church, Ph.D.; Mark Kirstein PharmD; Jatinder Lamba, PhD; Robert Kratzke, MD; Vipin Kumar, Ph.D.; Stephen Hecht, Ph.D.
|
Cancer Ctr, Medical, Public Health, Pharmacy, Comptuer Science
|
$238,521
|
|
Receptor recognition and cross-species infections by human coronaviruses
|
Fang Li, PhD; Louis Mansky, PhD
|
Medical, Dentistry
|
$244,725
|
|
The Role of a Thiol-Based Compound, N-Acetylcysteine, in the Prevention of Reperfusion Injury following Percutaneous Coronary Intervention in the Settin gof Acute Myocardial Infarcation
|
Henning Schröder, PhD; Jay H. Traverse, MD, FACC
|
Pharmacy, Medical
|
$203,832
|
|
Development of Novel Gamma Lactam Based Small Molecules as Anticancer Agents
|
Venkatram R. Mereddy, Ph.D.; Patricia Scott, Ph.d.; Jon Rumbley, Ph.D., Teresa Rose-Hellekant, Ph.D.; Subhash C. Basak
|
Pharmacy, Medical
|
$200,000
|
|
Semi-automated assessment of Drug Induced Language Deficits
|
Susan E. Marino, PhD; Serguei Pakhomov, PhD; Apostolos P. Georgopoulous MD, PhD
|
Medical, Pharmacy
|
$249,988
|
|
Biomarkers to Investigate Ethnic Differences in Tobacco Carcinogenesis
|
Stephen S. Hecht, PhD; Sharon E. Murphy, PhD; Lisa A. Petesron, PhD
|
Medical, Public Health
|
$200,000
|
| |
|
FRD 2007 Grant Summary
|
|
Body composition in growth-retarded infants undergoing catch-up growth: Establishing in interdisciplinary working group on infant obesity and health
|
Ellen W. Demerath, PhD;
Julia Steinberger, MD
|
School of Public Health
Medical School
|
|
|
DNA-Protein Cross-linking in Carcinogenesis and Cancer Chemotherapy
|
Collin Campbell, PhD;
Natalia Tretyakova, PhD.
|
School Medicine
College of Pharmacy
|
|
|
Neural Stem Cell Responses to Viral Encephalitis
|
Maxim C-J. Cheeran, M.V.Sc., PhD;
Walter C. Low, PhD;
Dale Gregerson, PhD;
Anibal Armien, DVM
|
Medical School
Medical School
Medical School
College of Veterinary Medicine
|
|
|
Internet-Based Health Care Transition Program
|
Peter B.Scal, MD;
Ann E. Garwick, PhD, RN;
Keith J. Horvath PhD
|
Medical School,
School of Nursing,
School of Public Health
|
|
|
Intrathecal Delivery of Gene Therapeutics for the Treatment of Chronic Pain
|
Carolyn Fairbanks, PhD; R
Scott McIvor, PhD;
Lucy Vulchanova, PhD.
|
College of Pharmacy,
Medical School,
College of Veterinary Medicine
|
|
|
Using metagenomic approaches to evaluate the human and animal health risks associated with the use of a veterinary antibiotic
|
Randall Singer, DVM, MPVM, PhD;
Richard Isaacson, PhD;
George Maldonado, PhD,
Srinand Sreevfastsan, MVSc, MPH, PhD
|
College of Veterinary Medicine,
College of Veterinary Medicine,
School of Public Health,
College of Veterinary Medicine
|
|
| |
|
|
|
| FRD 2006 Grant Summary |
|
|
|
|
Design and Development of Drugs to Treat Vancomycin Resistant Microbial Pathogens
|
Ramaiah Muthyala, PhD, MBA
Gary Dunny, PhD
|
College of Pharmacy
Medical School
|
$199,068
|
|
Mindfulness Meditation versus Pharmacotherapy for Chronic Insomniac: A Pilot Study"
|
Cynthia Gross, PhD
Mary Jo Kreitzer, RN, PhD
Jennifer Schultz, PhD
Robert Patterson, PhD
Melanie Wall, PhD
|
College of Pharmacy
School of Nursing
Economics
Medical School
Public Health
|
$244,715
|
|
Pre-Clinical Studies of New Agents for Treating Pancreatic Cancer
|
David M. Ferguson, PhD
Hiroshi Hiasa, PhD, MS
|
College of Pharmacy
Medical School
|
$250,000
|
|
Impact of human APOBEC3 proteins on HIV-1 drug resistance
|
Reuben Harris, PhD
Louis Mansky, PhD
|
Medical School
College of Dentistry
|
$222,060
|
|
Proteomics and Pediatric Inflammatory Bowel Disease
|
Glenn Gourley, MD
Gary Nelsestuen, PhD
Baolin Wu
|
Medical School
Medical School
Public Health
|
$199,577
|
|
Self-regulation Treatment for Childhood Obesity
|
Kerri Boutelle, PhD
Lisa Harnack, DrPH
|
Medical School
Public Health
|
$219,081 |
| |
|
|
|
|
FRD 2005 Grant Summary
|
|
|
|
|
Design of Antitumor CAP-Dependent Translation Antagonists
|
Carston R. Wagner
Vitaly A. Polunovsky
Elizabeth A. Amin
|
Pharmacy
Med School
Chemistry
|
$209,630
|
|
The Impact of Health Information Exchange
|
Stuart M. Speedie.
Donald Connelly
Kevin Peterson
Bryan Dowd
John Kralewski
Bonnie Westra
Connie Delaney
|
Med School
Med School
Med School
Public Health
Public Health
Nursing
Nursing
|
$230,069
|
|
Examining how NAT Polymorphisms Affect Protein Structure, Activity and Stability
|
Kylie J. Walters
Patrick E. Hanna
Carston R. Wagner
Deanna Koepp
|
Med School
Pharmacy
Pharmacy
Med School
|
$214,315
|
|
Patient-Controlled Sedation Feasibility Study
|
Linda L. Chlan.
Craig R. Weinert
Debra Skaar
|
Nursing
Med School
Pharmacy
|
$91,169
|
|
Thalamic Mast Cells Inhibit HPA Activity
|
Alice A. Larson
William C. England
|
Vet Med
Med School
|
$205,088
|
|
Bioengineering of a Cardiac Autogrtaft on Cadaveric Extracellular Matrix
|
Har Ott
D. A. Taylor
Anthony Tobias
Susan Keirstead
|
Med School
Med School
Vet Med
Med School
|
$196,983
|
|
|
|
|
|
| FRD 2004 Grant Summary |
|
|
|
|
Integrative Analysis of Genomic and Proteomic Data
|
|
-School of Public Health, Biostatistics;
-Medical School, Biochemistry, Molecular Biology, and Biophysics
|
|
|
Development of a Novel Ex Vivo Bone Cancer Pain Model
|
Alvin Beitz
Donald Simone
Virginia Seybold
Laura Mauro
|
-College of Veterinary Medicine;
-School of Dentistry;
-Medical School, Neuroscience;
-College of Veterinary Medicine
|
|
| Twisted Gastrulation and Bone Formation |
Rajaram Gopalakrishnan
Anna Petryk
|
;-School of Dentistry;
-Medical School, Pediatrics
|
|
| A School-based Body Mass Index Screening Program: Phase II |
Martha Kubik
Jeremy Springer
Mary Story
|
-School of Nursing;
-Medical School, Family Medicine;
-School of Public Health, Epidemiology
|
|
| Human Brain Vascular Genomics |
Lester Drewes
James Cloyd
William Elmquist
Stephen Haines
Walter Hall
|
-Medical School, Biochemistry/Molecular Biology;
-College of Pharmacy;
-College of Pharmacy;
-Medical School, Neurosurgery
-Medical School, Neurosurgery
|
|
| Culture of Safety at the Microsystem Level: Impact on Patient Safety and Other Quality Outcomes |
William Riley
Bryan Dowd
Karyn Baum
Helen Hansen
|
-School of Public Health, Health Services Research and Policy;
-School of Public Health, Health Services Research and Policy;
-Medical School, Medicine;
-School of Nursing
|
|
| |
|
|
|
| FRD 2003 Grant Summary |
|
|
|
| Substrate Interactions with Drug Metabolizing Enzymes |
Timothy Tracy,
Hiroshi Matsuo |
Pharmacy,
Medical School |
$226,373 |
| Identification of Novel Key Genes for S. aureus Infections |
Yinduo Ji,
Pat Cleary,
Patrick Schlievert,
Doug Weiss |
Vet Pathobiology,
Vet Pathobiology,
Microbiology,
Microbiology |
$199,610 |
| Transposon mediated mutagenesis and gene discovery in ApcMin/+ tumorigenesis |
Robert Cormier,
David Largaespada,
Cathy Carlson |
UMD Biochem & Mol Biology,
Genetics Cell Biol & Devel,
Vet Diagnostic Med |
$199,850 |
| Glutathione Prodrug Therapy for Acute Lung Injury |
Imad Haddad,
Timothy Wiedmann |
Pediatrics,
Pharmacy |
$208,169 |
| Novel Genetic Techniques to Analyze Human and Animal Neuromuscular Disorders |
Laura Ranum,
Stephanie Valberg,
James Michelseon,
John Day |
Medicine,
Vet Med,
Vet Med,
Medicine |
$249,000 |
| Upper Extremity Aerobic Training for Critical Limb Ischemia |
Diane Treat-Jacobson,
Steven Santilli,
Arthur Leon,
Nigel Key |
Nursing,
Surgery,
Kinesiology,
Medicine |
$242,167 |
| Development of a Transgenic Cystic Fibrosis Pig |
Clifford Steer,
Betsy Kren,
Carlos Milla,
Warren Warwick,
Scott Fahrenkrug,
Scott Ogrady,
Ned Patterson,
Ava Trent |
Medicine,
Medicine,
Pediatrics,
Pediatrics,
Animal Sci,
Animal Sci,
Small Animal Clin Sci,
Clin/Pop Sci |
$249,921 |
| |
|
|
|
| FRD 2002 Grant Summary |
|
|
|
| Development and Testing of Formulations for Transtympanic Membrane Delivery of Antibiotics to the Middle Ear |
Ronald Sawchuck, Scott Giebink |
Pharmacy, Medical School |
$195,202 |
| Functional and Genomic Differences in Mononuclear Phagocytes that Predict Susceptibility to Johne's Disease |
Douglas Weiss, Alex Khortus |
Veterinary Medicine, Medical School |
$132,878 |
| Reversing Diabetes in Nonhuman Primates with Xenogeneic Porcine Islets |
Bernhard Hering, Michael Murtaugh |
Medical School, Veterinary Medicine |
$198,633 |
| Structural Dynamics of a Molecular Motor Involved in Virus Assembly |
Paul Jardine, David Thomas |
Dentistry, Medical School |
$197,767 |
| Family Process and Mental Disorders in Youths with Diabetes |
Joan Patterson, Dianne Neumark-Sztainer |
Public Health, Public Health |
$166,515 |
| Chemoenzymatic Synthesis of Ketolide Antibiotics |
Robert Fecik, David Sherman |
Pharmacy, Medical School |
$234,000 |
| |
|
|
|
| FRD 2001 Grant Summary |
|
|
|
| Effects of Zyban and Cognitive Behavioral Therapy on Stress Reactivity and Smoking Withdrawal Symptoms |
Lisa Brauer |
Medical School |
$168,862 |
| Preventive Interventions for Anxious Children |
Gail Bernstein |
Medical School |
$199,824 |
| Novel Lentivirus Vectors for Gene Therapy |
Scott McIvor, Michael Murtaugh |
Medical School, Veterinary Medicine |
$182,753 |
| Complement Regulation of Cellular Immunity in Asthma |
Agustin Dalmasso |
Medical School |
$239,160 |
| Stem Cells and the Nervous System |
Al Beitz |
Veterinary Medicine |
$198,015 |
| Role of Sex Hormones in Immune-mediated Central Nervous SystemDemyelination |
Moses Njenga |
Veterinary Medicine |
$215,914 |
| |
|
|
|
| FRD 2000 Grant Summary |
|
|
|
| Genetic Correction of Hematopoietic Stem Cells in Patients with Fanconi Anemia |
John Wagner |
Medicine |
$187,744 |
| |
Catherine Verfaillie |
Medicine |
|
| |
Pamela Jacobson |
Pharmacy |
|
| Design of opioid analgesics devoid of tolerance and addiction potential |
Ping-Yee Law |
Medicine |
$266,570 |
| |
Philip Portoghese |
Phamarcy |
|
| Impact of Mindfulness-Based Stress Reduction on Symptom Management in Kidney Transplant Recipients |
Cynthia Gross |
Pharmacy |
$195,329 |
| |
Marshall Hertz |
Medicine |
|
| |
Mary Jo Kreitzer |
Nursing |
|
| Regulation of ADP-Ribosyl Cyclase in Smooth Muscle |
Mathur Kannan |
Veterinary |
$176,194 |
| |
Michael Murtaugh |
Veterinary |
|
| |
Timothy Walseth |
Medicine |
|
| |
David Cornfield |
Medicine |
|
| Canine Bone Marrow-Derived Multipotent Adult Progenitor Cells: Isolation and Characterization |
Timothy O'Brien |
Veterinary |
$200,000 |
| |
Catherine Verfaillie |
Medicine |
|
| Role of Natriuretic Peptides in Auditory System Function |
Janet Fitzakerley |
Medicine (D) |
$102,928 |
| |
Eric Javel |
Medicine |
|
| |
Steven Juhn |
Medicine |
|
| |
George Trachte |
Medicine (D) |
|
| Shiga-toxin Producing Escherichia coli (STEC): Occurrence in Dairy Cattle and Risk Factors for Human Infections in Agricultural and Urban Areas |
Craig Hedberg |
Public Health |
$168,922 |
| |
Jeffrey Bender |
Veterinary |
|
| |
|
|
|
| FRD 1999 Grant Summary |
|
|
|
| Novel Transposon for Gene Delivery |
David Largaespada (Stephen Ekker/ Carston Wagner/ Scott McIvor/ Perry Hackett) |
Medical School/Pharmacy |
$200,000 |
| Vascular Biomechanics in Plaque Rupture |
Antheunis Versluis (Alan Bank/ Daniel Mooradian) |
Dentistry/Medical School |
$199,963 |
| Porcine Cytomegalovirus Risk for Xenotransplantation |
Thomas Molitor (Barbara Potts/ Walter Low/ Bernard Hering/ Kurt Rossow) |
Veterinary Medicine/Medical School |
$169,022 |
| Structural Biology in the New Millennium |
Deborah Kallick/ David Thomas |
Pharmacy/ Medical School |
$200,000 |
| Microbial Pathogen Genome Sequencing |
Vivek Kapur (Ernie Retzel) |
Veterinary MedicineMedical School |
$200,000 |
| Genomic Science and Technology in Hepatic Tissue Engineering |
Larry Schook replaced Craig Beattie (Wei-Shou Hu/ Linda Hansen/ Rory Remmel/ Mark Rutherford/ Tim Sielaff) |
Medical School/PharmacyVeterinary Medicine |
$200,000 |
| Mechanisms of Antiviral Activity of Betulin and Its Derivatives |
Kendall Wallace (Stephen Rice/ Robert Carlson) |
School of Medicine-D/Medical School |
$200,000 |
| Gamete Cryopreservation and Assisted Reproduction |
Ken Roberts (Mats Troedsson/ David Hamilton/ John Bischof/ Chris De Jonge) |
Medical School |
$199,650 |
| |
|
|
|
| FRD 1998 Grant Summary |
|
|
|
| Interdisiciplinary Research on the Health Effects of Airborne Particulate Matter |
Ken Sexton |
Public Health |
$298,740 |
| Development and Testing of a Novel System for Prompting and Monitoring Exercise Behavior in Older Adults |
Jean Wyman |
Medical School/Pharmacy/Nursing |
$150,000 |
| Targeted Immunotherapy for the Treatment of Cancer |
Jeffrey Miller |
Medical School/Veterinary Medicine |
$298,924 |
| Control of Spinal Cord Synaptic Plasticity |
George Wilcox |
Dental School/Pharmacy/Medical School |
$150,000 |
| Stem Cell Gene Therapy for Chronic Myelogenous Leukemia |
Catherine Verfaillie |
Pharmacy/Medical School |
$299,006 |
| |
|
|
|
| FRD 1997 Grant Summary |
|
|
|
| Immunology |
Matt Mescher |
Medical School |
$300,000 |
| Transgenic Animal Facility |
Harry Orr |
Medical School |
$185,000 |
| Liquid Chromatography/Mass Spectrometry |
Rory Remmel |
Pharmacy |
$110,000 |
| Multiphoton Microscope |
Patrick Mantyh |
Dental School |
$185,000 |
| Duluth Based Research Initiatives |
Richard Ziegler |
School of Medicine (D) |
$20,000 |
| Neurobiology |
Jim Cloyd |
Pharmacy |
$300,000 |
| Neurosciences |
Costantino Iadecola |
Medical School |
$300,000 |
| Advanced Therapies |
Phil McGlave/William Gleason |
Medical School |
$300,000 |
| Biomedical Engineering |
Dan Mooradian/ Ron McGlennen |
Medical School |
$300,000 |
| Genetics |
Larry Schook |
Veterinary Medicine |
$300,000 |
| |
|
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|
